Research Guides

Research Literacy

How to read published research: study models, control groups and the limits of what a single result can show.

Research Literacy

Cosmetic Signal Peptides: Reading the Argireline and KTTKS Literature

A reference for laboratory teams on two short cosmetic-ingredient peptides: acetyl hexapeptide-8 (marketed as Argireline) and the collagen-derived pentapeptide KTTKS. It covers nomenclature, how they were first described, what penetration and analytical studies measured, and why concentrations across papers differ.

5 min read

Research Literacy

Dihexa: Reading a Compound's Record When Related Papers Are Retracted

A literacy case study for laboratory teams: dihexa, a modified angiotensin IV-derived compound, has a thin primary literature in which a founding paper carries an expression of concern and two related papers from the same group were retracted in 2025. This guide shows how to trace and weigh such a record.

5 min read

Research Literacy

DSIP: A Peptide Named for an Effect It Never Pinned Down

A reference profile of delta sleep-inducing peptide (DSIP) for laboratory teams: the original 1977 isolation and sequence, why a name can promise more than the data show, the unrelated 77-residue protein later recognized by DSIP antibodies, and how to read the literature.

4 min read

Research Literacy

Reading a PubChem Compound Record: Identifiers, Synonyms and Pitfalls

PubChem is one of the most-used public chemistry databases, and its records are often cited for research peptides. This guide explains how PubChem is organised (Substance, Compound and BioAssay), what CIDs, SIDs and CAS Registry Numbers are, how structure standardisation works, why many peptides have no 3D conformer, and the common pitfalls when matching a record to a vial.

7 min read

Research Literacy

Small Studies, Big Claims: Sample Size, Statistical Power and Reporting Quality

Much of the peptide literature rests on small studies. This guide explains, from well-known methodology papers, what statistical power is, why low power both misses real effects and inflates the ones it finds, which features of a research field make findings less reliable, and how the ARRIVE 2.0 reporting guidelines help you judge an animal study.

8 min read

Research Literacy

What Peptide Names Mean: Decoding Research Peptide Names

A guide to how research peptide names are formed, from one-letter amino-acid codes and acronyms to lab codes, parent-molecule names and official nonproprietary name stems, and why a name never tells you what a compound does.

4 min read